Human T-lymphotropic virus kind 1 (HTLV-1) provirus expression is especially directed by Tax-responsive components (TRE) inside the lengthy terminal repeats (LTR). Mutations in TRE can cut back provirus expression and since a excessive proviral load (PVL) is a danger issue for the event of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), we evaluated polymorphisms within the 5′ LTR and the affiliation with PVL and illness development.
HTLV-1 LTR and tax sequences derived from asymptomatic carriers (AC) and HAM/TSP sufferers adopted in a longitudinal examine had been analysed based on PVL and medical severity. People contaminated with HTLV-1 presenting the canonical TRE, contemplating pressure ATK-1 because the consensus, displayed sustained larger PVL. In contrast, an LTR A125G mutation in TRE was related to barely diminished PVL solely in HAM/TSP sufferers, though it didn’t affect the pace of illness development.
Furthermore, this polymorphism was frequent in Latin American strains of the HTLV-1 Cosmopolitan Transcontinental subtype. Due to this fact, polymorphisms within the 5′ TRE of HTLV-1 could symbolize one of many components influencing PVL in HAM/TSP sufferers, particularly within the Latin American inhabitants. Certainly, larger PVL within the peripheral blood has been related to an elevated inflammatory exercise within the spinal twine and to a poorer prognosis in HAM/TSP. Nevertheless, this occasion was not related to TRE polymorphisms.
HTLV-1 encephalitis
A 53-year-old lady developed subacute onset of higher limb weak point, sensory loss and cerebellar dysfunction. She was recognized to have human T-lymphotropic virus kind 1 (HTLV-1)-associated myelopathy. MR scan of the mind confirmed intensive T2 hyperintensity inside the deep and subcortical white matter, with punctate distinction enhancement.
Cerebrospinal fluid (CSF) was lymphocytic with very excessive ranges of HTLV-1 provirus in each CSF and peripheral blood lymphocytes. We identified HTLV-1 encephalomyelitis and began high-dose methylprednisolone adopted by a gradual corticosteroid taper. She recovered effectively and regained practical independence within the higher limbs.
Neurological manifestations of HTLV-1 an infection lengthen past classical ‘tropical spastic paraparesis’ and are under-recognised. We assessment the literature on HTLV-1 encephalitis and focus on its prognosis and administration.
HTLV-1 an infection in acute t- lymphocytic leukemia/lymphoma
Grownup T- lymphocyte leukemia/ lymphoma (ATLL), described by Uchiyama et al. in 1977, is a definite neoplasia of peripheral T-lymphocytes attributable to human T-cell lymphotropic virus kind 1 (HTLV-1). The authors describe the case of a 75-year-old feminine affected person who offered with fever, chills, and altered psychological standing.
The peripheral blood morphology confirmed massive atypical lymphocytes with multilobed nuclei and circulate cytometry per ATLL. The authors focus on the pathophysiology, differential prognosis, and subtypes of ATLL along with the diagnostic method utilizing circulate cytometry when bone marrow biopsy is just not accessible and modalities of therapy.
Involvement of EZH2 inhibition in lenalidomide and pomalidomide-mediated progress suppression in HTLV-1-infected cells
Immunomodulatory imide medication (IMiDs), akin to lenalidomide and pomalidomide, exert pleiotropic results, e.g., antitumor results in a number of myeloma, by binding the protein Cereblon and altering its substrate specificity.
Lenalidomide is authorised for the therapy of grownup T-cell leukemia/lymphoma (ATL) attributable to human T-cell leukemia virus kind 1 (HTLV-1), though the exact mechanisms accountable for its effectiveness haven’t been totally elucidated.
Right here, we used HTLV-1-infected cell traces to research how IMiDs exert anti-ATL results. In three of 4 examined HTLV-1-infected cell traces, the cells handled with lenalidomide or pomalidomide exhibited gentle progress suppression with out apoptosis, which was related to decreased IRF4, c-Myc, and phosphorylated STAT3 ranges in addition to enhanced SOCS3 expression. Moreover, the degrees of enhancer of zeste homolog 2 (EZH2) and trimethyl histone three Lys27 (H3K27me3) had been decreased following IMiD therapy in all three vulnerable cell traces.
An IMiD-mediated discount of EZH2 and H3K27me3 ranges was additionally noticed in a a number of myeloma cell line. Moreover, therapy with an EZH2-inhibitor reproduced the IMiD-mediated results in HTLV-1-infected cells and a number of myeloma cells. These findings strongly recommend {that a} discount of EZH2 expression is concerned within the mechanism underlying the antitumor results of IMiD.
HTLV-2 Encoded Antisense Protein APH-2 Suppresses HIV-1 Replication
Antisense protein of Human T-cell Leukemia Virus Sort 2 (HTLV-2), additionally referred to as APH-2, negatively regulates the HTLV-2 and helps the virus to keep up latency through scheming the transcription. Regardless of the outstanding prevalence of HTLV-2/HIV-1 co-infection, the function of APH-2 influencing HIV-1 replication kinetics is poorly understood and wishes investigation.
On this examine, we investigated the believable function of APH-2 regulating HIV-1 replication. Herein, we report that the overexpression of APH-2 not solely hampered the discharge of HIV-1 pNL4.three from 293T cells in a dose-dependent method but in addition affected the mobile gag expression. The same and constant impact of APH-2 overexpression was additionally noticed in case of HIV-1 gag expression vector HXB2 pGag-EGFP.
APH-2 overexpression additionally inhibited the power of HIV-1 Tat to transactivate the HIV-1 LTR-driven expression of luciferase. Moreover, the introduction of mutations within the IXXLL motif on the N-terminal area of APH-2 reverted the inhibitory impact on HIV-1 Tat-mediated transcription, suggesting the attainable function of this motif in the direction of the downregulation of Tat-mediated transactivation.
General, these findings point out that the HTLV-2 APH-2 could have an effect on the HIV-1 replication at a number of ranges by (a) inhibiting the Tat-mediated transactivation and (b) hampering the virus launch by affecting the mobile gag expression.
An Epitope Platform for Protected and Efficient HTLV-1-Immunization: Potential Purposes for mRNA and Peptide-Based mostly Vaccines
Human T-cell lymphotropic virus kind 1 (HTLV-1) an infection impacts hundreds of thousands of people worldwide and might result in extreme leukemia, myelopathy/tropical spastic paraparesis, and quite a few different issues.
Pursuing a protected and efficient immunotherapeutic method, we in contrast the viral polyprotein and the human proteome with a sliding window method with a view to determine oligopeptide sequences distinctive to the virus. The immunological relevance of the viral distinctive oligopeptides was assessed by looking out them within the immune epitope database (IEDB). We discovered that HTLV-1 has 15 peptide stretches every consisting of uniquely viral non-human pentapeptides that are ideally suited candidate for a protected and efficient anti-HTLV-1 vaccine.
Recombinant HTLV gp21 Protein (Coating) [2B3A] |
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| VAng-Lsx0306-inquire | Creative Biolabs | inquire | Ask for price |
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Description: HTLV gp21 Antigen [2B3A], Recombinant antigen. |
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Recombinant HTLV gp21 Protein (Detection) [PV112] |
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| VAng-Lsx0307-inquire | Creative Biolabs | inquire | Ask for price |
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Description: HTLV gp21 Antigen [PV112], Recombinant antigen. |
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Recombinant HIV HTLV-1 gp21 Protein, GST, E.coli-100ug |
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| QP12354-100ug | EnQuireBio | 100ug | EUR 261.6 |
Recombinant HIV HTLV-1 gp21 Protein, GST, E.coli-1mg |
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| QP12354-1mg | EnQuireBio | 1mg | EUR 1513.2 |
Recombinant HIV HTLV-1 gp21 Protein, GST, E.coli-500ug |
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| QP12354-500ug | EnQuireBio | 500ug | EUR 795.6 |
Recombinant HTLV-I Gp21 (a.a. 351-404), GST Tagged |
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| DAG443 | Creative Diagnostics | 100ug | EUR 823.2 |
HTLV1 gp21 protein |
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| 30-044001 | Fitzgerald | 100 ug | EUR 758.4 |
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Description: Purified recombinant HTLV1 gp21 protein |
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HTLV1 gp21 protein |
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| 30-044001-LQ | Fitzgerald | 100 ug | EUR 758.4 |
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Description: Purified recombinant HTLV1 gp21 protein |
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HTLV1 gp21 protein (HRP) |
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| 65-044002 | Fitzgerald | 50 ug | EUR 853.2 |
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Description: Purified recombinant HTLV1 gp21 (HRP) |
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HTLV1 gp21 protein (FITC) |
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| 65-044003 | Fitzgerald | 50 ug | EUR 418.8 |
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Description: Purified recombinant HTLV1 gp21 (FITC) |
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Recombinant HTLV-1 Envelope |
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| 7-07753 | CHI Scientific | 100µg | Ask for price |
Recombinant HTLV-1 Envelope |
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| 7-07754 | CHI Scientific | 500µg | Ask for price |
Recombinant HTLV-1 Envelope |
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| 7-07755 | CHI Scientific | 1000µg | Ask for price |
Recombinant HTLV-1 p24 |
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| 7-07759 | CHI Scientific | 100µg | Ask for price |
Recombinant HTLV-1 p24 |
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| 7-07760 | CHI Scientific | 500µg | Ask for price |
Recombinant HTLV-1 p24 |
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| 7-07761 | CHI Scientific | 1000µg | Ask for price |
Recombinant HTLV-1 gp46 |
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| 7-07768 | CHI Scientific | 100µg | Ask for price |
Recombinant HTLV-1 gp46 |
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| 7-07769 | CHI Scientific | 500µg | Ask for price |
Recombinant HTLV-1 gp46 |
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| 7-07770 | CHI Scientific | 1000µg | Ask for price |
Recombinant HTLV-1 Mosaic |
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| 7-07771 | CHI Scientific | 100µg | Ask for price |
Recombinant HTLV-1 Mosaic |
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| 7-07772 | CHI Scientific | 500µg | Ask for price |
Recombinant HTLV-1 Mosaic |
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| 7-07773 | CHI Scientific | 1000µg | Ask for price |
HTLV-1 TAX Antibody |
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| 20-abx137064 | Abbexa |
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HTLV-1 Envelope Protein |
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| 20-abx260142 | Abbexa |
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HTLV-1 p24 Protein |
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| 20-abx260271 | Abbexa |
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HTLV-1 gp46 Protein |
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| 20-abx260285 | Abbexa |
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HTLV-1 Mosaic Protein |
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| 20-abx260286 | Abbexa |
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HTLV 1 ELISA Kit |
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| VArk-Lsx012 | Creative Biolabs | 1 KIT | Ask for price |
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Description: Used for analyzing the presence of the human T-Cell lymphotropic viruses. |
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Recombinant HTLV-1 Protein |
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| VAng-Lsx0308-inquire | Creative Biolabs | inquire | Ask for price |
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Description: HTLV type 1, recombinant protein from E. coli. |
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Recombinant HTLV-1 p24 Core |
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| 7-07756 | CHI Scientific | 100µg | Ask for price |
Recombinant HTLV-1 p24 Core |
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| 7-07757 | CHI Scientific | 500µg | Ask for price |
Recombinant HTLV-1 p24 Core |
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| 7-07758 | CHI Scientific | 1000µg | Ask for price |
Tax8, HTLV - 1 (12 - 19) |
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| 5-02002 | CHI Scientific | 4 x 5mg | Ask for price |
Tax9, HTLV - 1 (11 - 19) |
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| 5-02003 | CHI Scientific | 4 x 5mg | Ask for price |
HTLV-1 gp46 recombinant protein |
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| 00701-V-01mg | Virogen | 0,1 mg | EUR 321 |
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Description: HTLV-1 gp46 recombinant protein |
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HTLV-1 gp46 recombinant protein |
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| 00701-V-1000ug | Virogen | 1000 ug | EUR 1539 |
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Description: HTLV-1 gp46 recombinant protein |
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HTLV-1 p24 Core Protein |
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| 20-abx260143 | Abbexa |
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HTLV type 1 Glycoprotein 46 |
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| DAG-P2817 | Creative Diagnostics | 100 µg | EUR 868.8 |
Porcine HTLV-1 ELISA Kit |
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| EPH0319 | Abclonal | 96Tests | EUR 625.2 |
Rabbit HTLV-1 ELISA Kit |
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| ERTH0319 | Abclonal | 96Tests | EUR 625.2 |
Rat HTLV-1 ELISA Kit |
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| ERH0319 | Abclonal | 96Tests | EUR 625.2 |
Mouse HTLV-1 ELISA Kit |
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| EMH0319 | Abclonal | 96Tests | EUR 625.2 |
Human HTLV-1 ELISA Kit |
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| EHH0319 | Abclonal | 96Tests | EUR 625.2 |
Goat HTLV-1 ELISA Kit |
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| EGTH0319 | Abclonal | 96Tests | EUR 625.2 |
Bovine HTLV-1 ELISA Kit |
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| EBH0319 | Abclonal | 96Tests | EUR 625.2 |
Canine HTLV-1 ELISA Kit |
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| ECH0319 | Abclonal | 96Tests | EUR 625.2 |
Anserine HTLV-1 ELISA Kit |
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| EAH0319 | Abclonal | 96Tests | EUR 625.2 |
HTLV-1 Tax (11-19) |
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| H-6096.0001 | Bachem | 1.0mg | EUR 138 |
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Description: Sum Formula: C56H79N9O12; CAS# [141677-18-1] net |
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HTLV-1 Tax (11-19) |
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| H-6096.0005 | Bachem | 5.0mg | EUR 441.6 |
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Description: Sum Formula: C56H79N9O12; CAS# [141677-18-1] net |
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HTLV 1/2 ELISA Kit |
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| VArk-Lsx011 | Creative Biolabs | 1 KIT | Ask for price |
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Description: Used for analyzing the presence of the human T-Cell lymphotropic viruses. |
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Recombinant (E.Coli) HTLV-1 Envelope |
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| RP-539 | Alpha Diagnostics | 100 ug | EUR 343.2 |
Recombinant (E.Coli) HTLV-1 gp46 |
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| RP-575 | Alpha Diagnostics | 100 ug | EUR 343.2 |
Recombinant HTLV-1 Mosaic Protein |
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| VAng-Lsx0310-inquire | Creative Biolabs | inquire | Ask for price |
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Description: HTLV type 1 Mosaic Protein, recombinant protein from E. coli. |
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Recombinant HTLV-1 E Protein |
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| VAng-Lsx0321-inquire | Creative Biolabs | inquire | Ask for price |
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Description: HTLV type 1 Envelope, recombinant protein from E. coli. |
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HTLV-1 virus mosaic recombinant antigen |
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| 00205-V-01mg | Virogen | 0,1 mg | EUR 321 |
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Description: HTLV-1 virus mosaic recombinant antigen a.a. 374-400/190-207. |
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HTLV-1 virus mosaic recombinant antigen |
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| 00205-V-1000ug | Virogen | 1000 ug | EUR 1539 |
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Description: HTLV-1 virus mosaic recombinant antigen a.a. 374-400/190-207. |
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Tax9, HTLV 1 (11 19) Peptide |
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| 20-abx266138 | Abbexa |
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Guinea Pig HTLV-1 ELISA Kit |
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| EGH0319 | Abclonal | 96Tests | EUR 625.2 |
Recombinant (E.Coli) HTLV-1 p24 Core |
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| RP-540 | Alpha Diagnostics | 100 ug | EUR 343.2 |
Recombinant HTLV-1 gag p19 Protein |
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| VAng-Lsx7388-100g | Creative Biolabs | 100 µg | EUR 2193.6 |
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Description: HTLV type 1 gag p19, recombinant protein from yeast. |
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Recombinant HTLV-1 P24 Core Protein |
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| VAng-Lsx0313-100g | Creative Biolabs | 100 µg | EUR 975.6 |
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Description: HTLV type 1 P24 Core, recombinant protein from E. coli. |
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Recombinant HTLV-1 P24 Core Protein |
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| VAng-Lsx0313-1mg | Creative Biolabs | 1 mg | EUR 4104 |
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Description: HTLV type 1 P24 Core, recombinant protein from E. coli. |
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Recombinant HTLV-1 P24 Protein [His] |
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| VAng-Lsx0314-1mgEcoli | Creative Biolabs | 1 mg (E. coli) | EUR 1126.8 |
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Description: HTLV-1 P24 Protein [His], recombinant protein from E. coli. |
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Recombinant HTLV-1 gp 46 Protein |
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| VAng-Lsx0319-100g | Creative Biolabs | 100 µg | EUR 2212.8 |
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Description: HTLV type 1 Glycoprotein 46, recombinant protein from E. coli. |
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Recombinant HTLV-1 E 701 Protein |
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| VAng-Lsx0322-50g | Creative Biolabs | 50 µg | EUR 2104.8 |
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Description: HTLV type 1 Envelope 701, recombinant protein from E. coli. |
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Recombinant HTLV-I+II |
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| 7-07762 | CHI Scientific | 5µg | Ask for price |
Recombinant HTLV-I+II |
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| 7-07763 | CHI Scientific | 20µg | Ask for price |
Recombinant HTLV-I+II |
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| 7-07764 | CHI Scientific | 1mg | Ask for price |
HTLV-I Env. Protein |
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| abx060597-1mg | Abbexa | 1 mg | EUR 1612.8 |
HTLV I gp46 Protein |
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| abx060599-100ug | Abbexa | 100 ug | EUR 811.2 |
HTLV I p24 Protein |
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| abx060600-1mg | Abbexa | 1 mg | EUR 1779.6 |
HTLV Mosaic protein [GST] |
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| DAG1572 | Creative Diagnostics | 100 µg | EUR 774 |
Recombinant HTLV P24 Protein |
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| VAng-Lsx0305-inquire | Creative Biolabs | inquire | Ask for price |
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Description: HTLV P24, recombinant protein from E. coli. |
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Recombinant HTLV-2 Protein |
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| VAng-Lsx0309-inquire | Creative Biolabs | inquire | Ask for price |
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Description: HTLV type 2, recombinant protein from E. coli. |
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Tax8, HTLV - 1 (12 - 19) (AA: Leu-Phe-Gly-Tyr-Pro-Val-Tyr-Val) (MW: 957.15) |
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| SP-86611-1 | Alpha Diagnostics | 1 mg | EUR 196.8 |
Recombinant (E.Coli, GST tag) HTLV-1 Mosaic |
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| RP-578 | Alpha Diagnostics | 100 ug | EUR 343.2 |
Histone H3 Methylation Antibody Panel Pack I – Active Genes |
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| C10000 | EpiGentek |
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Histone H3 Methylation Antibody Panel Pack I – Repression Genes |
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| C10001 | EpiGentek |
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Histone H3 Methylation Antibody Panel Pack II – Active Genes |
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| C10002 | EpiGentek |
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Histone H3 Methylation Antibody Panel Pack II – Repression Genes |
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| C10003 | EpiGentek |
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Histone H3 Methylation Antibody Panel Pack III – Active Genes |
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| C10004 | EpiGentek |
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Histone H3K4 Methylation Antibody Panel Pack |
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| C10005 | EpiGentek |
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Histone H3K9 Methylation Antibody Panel Pack |
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| C10006 | EpiGentek |
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Histone H3K27 Methylation Antibody Panel Pack |
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| C10007 | EpiGentek |
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Histone H3K36 Methylation Antibody Panel Pack |
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| C10008 | EpiGentek |
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Histone H3K79 Methylation Antibody Panel Pack |
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| C10009 | EpiGentek |
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Histone H3 Acetylation Antibody Panel Pack I |
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| C10010 | EpiGentek |
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Histone H3 Acetylation Antibody Panel Pack II |
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| C10011 | EpiGentek |
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Histone H4K20 Methylation Antibody Panel Pack |
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| C10012 | EpiGentek |
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Histone H4 Acetylation Antibody Panel Pack |
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| C10013 | EpiGentek |
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Histone H3 Phosphorylation Antibody Panel Pack |
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| C10014 | EpiGentek |
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Histone H3R2 Methylation Antibody Panel Pack |
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| C10015 | EpiGentek |
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Histone H3R8 Methylation Antibody Panel Pack |
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| C10016 | EpiGentek |
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Histone H3R17 Methylation Antibody Panel Pack |
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| C10017 | EpiGentek |
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Histone H3R26 Methylation Antibody Panel Pack |
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| C10018 | EpiGentek |
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Histone H4R3 Methylation Antibody Panel Pack |
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| C10019 | EpiGentek |
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DNA Methylation Antibody Panel Pack I |
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| C20000 | EpiGentek |
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DNMT3A Protein |
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| E11000 | EpiGentek |
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TET1 Protein (Active) |
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| E12002 | EpiGentek |
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DNMT3B Protein |
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| E14000 | EpiGentek |
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DNMT1 Protein |
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| E15000 | EpiGentek |
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HDAC1 Protein |
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| E24002 | EpiGentek |
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HDAC10 Protein |
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| E24003 | EpiGentek |
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HDAC11 Protein |
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| E24004 | EpiGentek |
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HDAC2 Protein |
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| E24005 | EpiGentek |
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HDAC3 Protein |
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| E24006 | EpiGentek |
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HDAC4 Protein |
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| E24007 | EpiGentek |
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HDAC5 Protein |
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| E24008 | EpiGentek |
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HDAC6 Protein |
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| E24009 | EpiGentek |
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HDAC7 Protein |
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| E24010 | EpiGentek |
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HDAC8 Protein |
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| E24011 | EpiGentek |
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HDAC9 Protein |
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| E24012 | EpiGentek |
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H3F3A Protein |
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| E35003 | EpiGentek |
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H4 Protein |
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| E35005 | EpiGentek |
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SOD1 Protein |
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| E70000 | EpiGentek |
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Goat Anti-Rabbit Secondary Antibody, Biotin Conjugated |
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| A12001 | EpiGentek |
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Goat Anti-Rat Secondary Antibody, Biotin Conjugated |
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| A12002 | EpiGentek |
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HRP-Goat Anti-Mouse Secondary Antibody |
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| A12003 | EpiGentek |
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HRP-Goat Anti-Rabbit Secondary Antibody |
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| A12004 | EpiGentek |
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EpiMag HT (96-Well) Magnetic Separator |
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| Q10002 | EpiGentek |
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EpiMag 96-Well Microplate (5/pack) |
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| Q10003 | EpiGentek |
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Human Genomic DNA |
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| X11000 | EpiGentek |
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Human Brain Genomic DNA |
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| X11001 | EpiGentek |
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Human T-Lymphotropic Virus 1 (HTLV-1) ELISA Kit |
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| abx052972-96tests | Abbexa | 96 tests | EUR 801.6 |
HTLV type 1 Active p24 (aa 314 - 344) |
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| DAG-P2586 | Creative Diagnostics | 200 µg | EUR 868.8 |
HTLV-I Envelope Recombinant Antigen |
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| 00203-V-01mg | Virogen | 0,1 mg | EUR 321 |
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Description: HLTV-I envelope recombinant antigen. C-terminus of gp-46 and most of p21. |
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HTLV-I Envelope Recombinant Antigen |
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| 00203-V-1000ug | Virogen | 1000 ug | EUR 1539 |
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Description: HLTV-I envelope recombinant antigen. C-terminus of gp-46 and most of p21. |
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HTLV Glycoprotein 46 Mosaic protein |
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| DAG1571 | Creative Diagnostics | 100 µg | EUR 774 |
Recombinant HTLV Mosaic Protein [GST] |
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| VAng-Lsx0304-inquire | Creative Biolabs | inquire | Ask for price |
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Description: Recombinant HTLV protein fused with GST at N-terminus was expressed in E. coli and purified by proprietary chromatographic technique. |
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ACE2, His-Tag Protein |
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| E80019 | EpiGentek |
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SARS-CoV-2 Spike S1 (13-665) Protein, Fc Fusion, Avi-tag |
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| E80020 | EpiGentek |
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SARS-CoV-2 Spike S1 (16-685) Protein, Avi-His-tag |
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| E80021 | EpiGentek |
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SARS-CoV-2 Spike S1 (16-685) Protein, Fc Fusion, Avi-tag |
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| E80022 | EpiGentek |
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SARS-CoV-2 Spike S1 RBD (V367F) Protein, Avi-His-tag |
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| E80023 | EpiGentek |
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SARS-CoV-2 Spike S1 RBD Protein, Avi-His-tag |
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| E80024 | EpiGentek |
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SARS-CoV-2 Spike S1 RBD Protein, Human Fc-Fusion, Avi-Tag |
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| E80025 | EpiGentek |
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SARS-CoV-2 Spike S1 RBD Protein, Mouse Fc-fusion |
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| E80026 | EpiGentek |
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SARS-CoV-2 Nucleocapsid Protein, Avi-His-tag |
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| E80027 | EpiGentek |
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Recombinant SARS-CoV-2 Spike Glycoprotein(S) (D614G), Partial |
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| E80028 | EpiGentek |
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Recombinant HIV HTLV-1 Envelope Protein, Untagged, E.coli-100ug |
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| QP12353-100ug | EnQuireBio | 100ug | EUR 261.6 |
Recombinant HIV HTLV-1 Envelope Protein, Untagged, E.coli-1mg |
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| QP12353-1mg | EnQuireBio | 1mg | EUR 1273.2 |
Recombinant HIV HTLV-1 Envelope Protein, Untagged, E.coli-500ug |
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| QP12353-500ug | EnQuireBio | 500ug | EUR 795.6 |
Recombinant HIV HTLV-1 mosaic Protein, Untagged, E.coli-100ug |
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| QP12356-100ug | EnQuireBio | 100ug | EUR 261.6 |
Recombinant HIV HTLV-1 mosaic Protein, Untagged, E.coli-1mg |
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| QP12356-1mg | EnQuireBio | 1mg | EUR 1513.2 |
Recombinant HIV HTLV-1 mosaic Protein, Untagged, E.coli-500ug |
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| QP12356-500ug | EnQuireBio | 500ug | EUR 795.6 |
Recombinant HIV HTLV-1 p24 Protein, Untagged, E.coli-100ug |
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| QP12357-100ug | EnQuireBio | 100ug | EUR 261.6 |
Recombinant HIV HTLV-1 p24 Protein, Untagged, E.coli-1mg |
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| QP12357-1mg | EnQuireBio | 1mg | EUR 1513.2 |
Recombinant HIV HTLV-1 p24 Protein, Untagged, E.coli-500ug |
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| QP12357-500ug | EnQuireBio | 500ug | EUR 795.6 |
Recombinant HTLV-1 E Protein Protein (aa 165-440) |
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| VAng-Lsx0317-inquire | Creative Biolabs | inquire | Ask for price |
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Description: HTLV type 1 Envelope protein (aa 165-440), recombinant protein from E. coli. |
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Recombinant HTLV-1 Active p24 Protein (aa 314-344) |
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| VAng-Lsx0318-inquire | Creative Biolabs | inquire | Ask for price |
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Description: HTLV type 1 Active p24 (aa 314-344), recombinant protein from E. coli. |
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Recombinant HTLV-1 gp 46 Protein (aa 165-440) |
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| VAng-Lsx0320-inquire | Creative Biolabs | inquire | Ask for price |
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Description: HTLV type 1 Glycoprotein 46 (aa 165-440), recombinant protein from E. coli. |
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HTLV-I p24 core recombinant antigen |
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| 00204-V-01mg | Virogen | 0,1 mg | EUR 321 |
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Description: HLTV-I p24 core recombinant antigen. |
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HTLV-I p24 core recombinant antigen |
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| 00204-V-1000ug | Virogen | 1000 ug | EUR 1539 |
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Description: HLTV-I p24 core recombinant antigen. |
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HTLV p19 Antigen ELISA (96 Determinations) |
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| 0801116 | Zeptometrix | 96T | EUR 827.52 |
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Description: Please contact Gentaur in order to receive the datasheet of the product. |
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Human T-lymphotropicvirus?,HTLV-?ELISA Kit |
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| 201-12-1810 | SunredBio | 96 tests | EUR 528 |
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Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
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Canine T-lymphotropicvirusⅠ,HTLV-ⅠELISA KIT |
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| QY-E70149 | Qayee Biotechnology | 96T | EUR 511.2 |
Recombinant HTLV gp 46 Mosaic Protein |
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| VAng-Lsx0303-inquire | Creative Biolabs | inquire | Ask for price |
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Description: Recombinant HTLV gp46 protein containing the gp46 immunodominant regions, 162-214 amino acids and 242-257 amino acids was expressed in E. coli and purified by proprietary chromatographic technique. |
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Recombinant HTLV-2 E 802 Protein |
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| VAng-Lsx0328-50g | Creative Biolabs | 50 µg | EUR 2004 |
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Description: HTLV-2 Envelope 802 Protein, recombinant protein from E. coli. |
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Methylamp 96 DNA Modification Kit |
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| P-1008 | EpiGentek |
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EpiQuik Nuclear Extraction Kit |
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| OP-0002 | EpiGentek |
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Nucleic Acid Isolation Enhancer (Glycogen Solution) |
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| R-1001 | EpiGentek |
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Methylamp PCR Enhancer |
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| R-1002 | EpiGentek |
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Streptavidin: HRP Conjugate |
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| R-1098 | EpiGentek |
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Streptavidin |
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| R-1100 | EpiGentek |
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Protease Inhibitor Cocktail |
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| R-1101 | EpiGentek |
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Streptavidin-Coated Strip Microwell Plate (Flat) |
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| R-1102 | EpiGentek |
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Certainly, experimentally validated HTLV-1 epitopes, as retrieved from the IEDB, include peptide sequences additionally current in an unlimited variety of human proteins, thus doubtlessly instituting the premise for cross-reactions. We discovered a possible for cross-reactivity between the virus and the human proteome and described an epitope platform for use with a view to keep away from it, thus acquiring efficient, particular, and protected immunization. Potential benefits for mRNA and peptide-based vaccine formulations are mentioned.
