The unfold of coronavirus illness 2019 (COVID-19) all through the world has resulted in anxious healthcare burdens and international well being crises. Creating an efficient measure to guard individuals from an infection is an pressing want. The blockage of interplay between angiotensin-converting enzyme 2 (ACE2) and S protein is taken into account an important goal for anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) medication.
A full-length ACE2 protein may very well be a possible drug to dam early entry of SARS-CoV-2 into host cells. On this examine, a therapeutic technique was developed through the use of extracellular vesicles (EVs) with decoy receptor ACE2 for neutralization of SARS-CoV-2.
The EVs embedded with engineered ACE2 (EVs-ACE2) had been ready; the EVs-ACE2 had been derived from an engineered cell line with steady ACE2 expression. The potential impact of the EVs-ACE2 on anti-SARS-CoV-2 was demonstrated by each in vitro and in vivo neutralization experiments utilizing the pseudovirus with the S protein (S-pseudovirus).
EVs-ACE2 can inhibit the an infection of S-pseudovirus in varied cells, and importantly, the mice handled with intranasal administration of EVs-ACE2 can suppress the entry of S-pseudovirus into the mucosal epithelium. Due to this fact, the intranasal EVs-ACE2 may very well be a preventive medication to guard from SARS-CoV-2 an infection. This EVs-based technique provides a possible path to COVID-19 drug growth.

Results of endurance coaching on the expression of host proteins concerned in SARS-CoV-2 cell entry in C57BL/6J mouse

The coronavirus illness 2019 (COVID-19) pandemic, brought on by extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is threatening individuals’s lives and impacting their well being. It’s nonetheless unclear whether or not individuals engaged in bodily exercise are at an elevated threat of SARS-CoV-2 an infection and extreme types of COVID-19. To be able to present knowledge to assist reply this query, we, subsequently, investigated the consequences of endurance coaching on the degrees of host proteins concerned in SARS-CoV-2 an infection in mice.
Eight-week-old C57BL/6J mice had been subjected to treadmill operating (17-25 m/min, 60-90 min, 5 classes/week, Eight weeks). After the intervention, the degrees of angiotensin-converting enzyme 2 (ACE2; host receptor for SARS-CoV-2), transmembrane protease serine 2 (TMPRSS2; host protease priming fusion of SARS-CoV-2 to host cell membranes), FURIN (host protease that promotes binding of SARS-CoV-2 to host receptors), and Neuropilin-1 (host coreceptor for SARS-CoV-2) had been measured in 10 organs that SARS-CoV-2 can infect (larynx, trachea, lung, coronary heart, jejunum, ileum, colon, liver, kidney, and testis).
Six organs (coronary heart, lung, jejunum, liver, trachea, and ileum) confirmed adjustments within the ranges of at the very least one of many proteins. Endurance coaching elevated ACE2 ranges in coronary heart (+66.4%), lung (+37.1%), jejunum (+24.7%) and liver (+27.4%), and FURIN in liver (+17.9%) tissue. In distinction, endurance coaching decreased Neuropilin-1 ranges in liver (-39.7%), trachea (-41.2%), and ileum (-39.7%), and TMPRSS2 in lung (-11.3%). Taken collectively, endurance coaching altered the degrees of host proteins concerned in SARS-CoV-2 cell entry in an organ-dependent method.

Histopathological options of SARS-CoV-2 an infection and relationships with organoid expertise

Coronavirus illness 2019 (COVID-19) following an infection by extreme acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has precipitated a world pandemic that’s nonetheless having critical results worldwide. This virus, which targets the lungs particularly, may injury different tissues. Angiotensin changing enzyme 2 (ACE-2) performs a key position in viral entry into host cells.
The presence of ACE-2 in varied tissues might allow viral an infection. Research of COVID-19 usually make use of postmortem tissues. Though this data supplies varied helpful outcomes, it is usually essential to conduct in vitro research to grasp optimum remedy approaches. As a result of the virus might present species-specific variations, in vitro applied sciences utilizing human cells are notably necessary.
Organoid applied sciences, three-dimensional constructions that may be obtained from human cells, are taking part in more and more necessary roles in research of SARS-CoV-2. This expertise provides a big benefit by way of mimicking in vivo tissue constructions and testing antiviral compounds. On this mini-review, we summarize research of SARS-CoV-2 utilizing each histopathological and organoid expertise approaches.

Serological evaluation of SARS-CoV-2 an infection in the course of the first wave of the pandemic in Louisville Kentucky

Serological assays meant for analysis, sero-epidemiologic evaluation, and measurement of protecting antibody titers upon an infection or vaccination are important for managing the SARS-CoV-2 pandemic. Serological assays measuring the antibody responses in opposition to SARS-CoV-2 antigens are available. Nonetheless, some lack acceptable traits to precisely measure SARS-CoV-2 antibodies titers and neutralization.
We developed an Enzyme-linked Immunosorbent Assay (ELISA) strategies for measuring IgG, IgA, and IgM responses to SARS-CoV-2, Spike (S), receptor binding area (RBD), and nucleocapsid (N) proteins. Efficiency traits of sensitivity and specificity have been outlined. ELISA outcomes present optimistic correlation with microneutralization and Plaque Discount Neutralization assays with infectious SARS-CoV-2.
Our ELISA was used to display screen healthcare employees in Louisville, KY in the course of the first wave of the native pandemic within the months of Could and July 2020. We discovered a seropositive charge of roughly 1.4% and a couple of.3%, respectively. Our analyses reveal a broad immune response amongst people and counsel some non-RBD particular S IgG and IgA antibodies neutralize SARS-CoV-2.

Cardiovascular tissue banking exercise throughout SARS-CoV-2 pandemic: evolution of nationwide protocols and Lombardy expertise

The worldwide pandemic outbreak attributable to extreme acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) has created unprecedented challenges for public well being companies. Lombardy, area of the Northern Italy, has been the primary space within the Western world whose organs and tissues procurement applications have needed to face the virus pandemic emergency.
We retrospectively collected and analyzed knowledge about cardiovascular tissues (CT) in 2019 and in 2020. We aimed to explain the speedy evolution of SARS-CoV-2 regulation legal guidelines for tissue donor’s choice and harvesting from February 2020 till January 2021. As anticipated the variety of CT donors in 2020 was considerably decrease than these of 2019 (66 vs. 99, p worth 0.02).
The entire variety of CT collected from donors have been 254 in 2019 and 206 in 2020 (p 0.28). Femoral arteries had been essentially the most required vascular tissues (55.5% in 2019 and 40% in 2020). Fifty-five and forty-eight pulmonary valves had been implanted in 2019 and 2020, respectively.

SARS2 siRNA

20-abx932472
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

anti-SARS2

YF-PA19458 50 ug
EUR 435.6
Description: Mouse polyclonal to SARS2

anti-SARS2

YF-PA19459 100 ul
EUR 483.6
Description: Rabbit polyclonal to SARS2

anti-SARS2

YF-PA19460 100 ug
EUR 483.6
Description: Rabbit polyclonal to SARS2

SARS2 Polyclonal Conjugated Antibody

C27672 100ul
EUR 476.4

SARS2 Rabbit pAb

A12297-100ul 100 ul
EUR 369.6

SARS2 Rabbit pAb

A12297-200ul 200 ul
EUR 550.8

SARS2 Rabbit pAb

A12297-20ul 20 ul
EUR 219.6

SARS2 Rabbit pAb

A12297-50ul 50 ul
EUR 267.6

SARS2 cloning plasmid

CSB-CL878836HU-10ug 10ug
EUR 451.2
Description: A cloning plasmid for the SARS2 gene.

Mouse SARS2 shRNA Plasmid

20-abx977615
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Human SARS2 shRNA Plasmid

20-abx960340
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

SARS2 ELISA KIT|Human

EF002720 96 Tests
EUR 826.8

SARS2 Recombinant Protein (Human)

RP027610 100 ug Ask for price

SARS2 Recombinant Protein (Rat)

RP227483 100 ug Ask for price

SARS2 Recombinant Protein (Mouse)

RP170015 100 ug Ask for price

Seryl-tRNA Synthetase 2, Mitochondrial (SARS2) Antibody

20-abx003637
  • EUR 493.20
  • EUR 710.40
  • 100 ul
  • 200 ul

Seryl-tRNA Synthetase 2, Mitochondrial (SARS2) Antibody

20-abx115487
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Seryl-tRNA Synthetase 2, Mitochondrial (SARS2) Antibody

20-abx126510
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Seryl-tRNA Synthetase 2, Mitochondrial (SARS2) Antibody

abx033708-400ul 400 ul
EUR 627.6

Seryl-tRNA Synthetase 2, Mitochondrial (SARS2) Antibody

abx033708-80l 80 µl
EUR 343.2

Seryl-tRNA Synthetase 2, Mitochondrial (SARS2) Antibody

abx237610-100ug 100 ug
EUR 610.8

Sars2 ORF Vector (Rat) (pORF)

ORF075829 1.0 ug DNA
EUR 607.2

Sars2 ORF Vector (Mouse) (pORF)

ORF056673 1.0 ug DNA
EUR 607.2

SARS2 ORF Vector (Human) (pORF)

ORF009204 1.0 ug DNA
EUR 114

SARS2 sgRNA CRISPR Lentivector set (Human)

K2089901 3 x 1.0 ug
EUR 406.8

Sars2 sgRNA CRISPR Lentivector set (Rat)

K6129701 3 x 1.0 ug
EUR 406.8

Sars2 sgRNA CRISPR Lentivector set (Mouse)

K3850001 3 x 1.0 ug
EUR 406.8

SARS2 sgRNA CRISPR Lentivector (Human) (Target 1)

K2089902 1.0 ug DNA
EUR 184.8

SARS2 sgRNA CRISPR Lentivector (Human) (Target 2)

K2089903 1.0 ug DNA
EUR 184.8

SARS2 sgRNA CRISPR Lentivector (Human) (Target 3)

K2089904 1.0 ug DNA
EUR 184.8

Sars2 sgRNA CRISPR Lentivector (Rat) (Target 1)

K6129702 1.0 ug DNA
EUR 184.8

Sars2 sgRNA CRISPR Lentivector (Rat) (Target 2)

K6129703 1.0 ug DNA
EUR 184.8

Sars2 sgRNA CRISPR Lentivector (Rat) (Target 3)

K6129704 1.0 ug DNA
EUR 184.8

Sars2 sgRNA CRISPR Lentivector (Mouse) (Target 1)

K3850002 1.0 ug DNA
EUR 184.8

Sars2 sgRNA CRISPR Lentivector (Mouse) (Target 2)

K3850003 1.0 ug DNA
EUR 184.8

Sars2 sgRNA CRISPR Lentivector (Mouse) (Target 3)

K3850004 1.0 ug DNA
EUR 184.8

SARS2 Protein Vector (Human) (pPB-C-His)

PV036813 500 ng
EUR 394.8

SARS2 Protein Vector (Human) (pPB-N-His)

PV036814 500 ng
EUR 394.8

SARS2 Protein Vector (Human) (pPM-C-HA)

PV036815 500 ng
EUR 394.8

SARS2 Protein Vector (Human) (pPM-C-His)

PV036816 500 ng
EUR 394.8

SARS2 Protein Vector (Mouse) (pPB-C-His)

PV226690 500 ng
EUR 723.6

SARS2 Protein Vector (Mouse) (pPB-N-His)

PV226691 500 ng
EUR 723.6

SARS2 Protein Vector (Mouse) (pPM-C-HA)

PV226692 500 ng
EUR 723.6

SARS2 Protein Vector (Mouse) (pPM-C-His)

PV226693 500 ng
EUR 723.6

Sars2 3'UTR GFP Stable Cell Line

TU269921 1.0 ml Ask for price

SARS2 3'UTR Luciferase Stable Cell Line

TU022597 1.0 ml
EUR 1672.8

Sars2 3'UTR Luciferase Stable Cell Line

TU219921 1.0 ml Ask for price

SARS2 3'UTR GFP Stable Cell Line

TU072597 1.0 ml
EUR 1672.8

Sars2 3'UTR GFP Stable Cell Line

TU168351 1.0 ml Ask for price

SARS2 Protein Vector (Rat) (pPB-C-His)

PV303314 500 ng
EUR 723.6

SARS2 Protein Vector (Rat) (pPB-N-His)

PV303315 500 ng
EUR 723.6

SARS2 Protein Vector (Rat) (pPM-C-HA)

PV303316 500 ng
EUR 723.6

SARS2 Protein Vector (Rat) (pPM-C-His)

PV303317 500 ng
EUR 723.6

Sars2 3'UTR Luciferase Stable Cell Line

TU118351 1.0 ml Ask for price

Bovine Seryl- tRNA synthetase, mitochondrial, SARS2 ELISA KIT

ELI-52192b 96 Tests
EUR 1113.6

Mouse Seryl- tRNA synthetase, mitochondrial, Sars2 ELISA KIT

ELI-41698m 96 Tests
EUR 1038

Human Seryl- tRNA synthetase, mitochondrial, SARS2 ELISA KIT

ELI-18558h 96 Tests
EUR 988.8

Human Seryl-tRNA Synthetase 2, Mitochondrial (SARS2) ELISA Kit

abx383028-96tests 96 tests
EUR 1093.2

SARS2 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)

K2089905 3 x 1.0 ug
EUR 451.2

Sars2 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)

K6129705 3 x 1.0 ug
EUR 451.2

Sars2 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)

K3850005 3 x 1.0 ug
EUR 451.2

SARS2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)

K2089906 1.0 ug DNA
EUR 200.4

SARS2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)

K2089907 1.0 ug DNA
EUR 200.4

SARS2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)

K2089908 1.0 ug DNA
EUR 200.4

Sars2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)

K6129706 1.0 ug DNA
EUR 200.4

Sars2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2)

K6129707 1.0 ug DNA
EUR 200.4

Sars2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 3)

K6129708 1.0 ug DNA
EUR 200.4

Sars2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)

K3850006 1.0 ug DNA
EUR 200.4

Sars2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)

K3850007 1.0 ug DNA
EUR 200.4

Sars2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)

K3850008 1.0 ug DNA
EUR 200.4

CD11b Antibody Antibody

ABD2911 100 ug
EUR 525.6

ASAP1 antibody Antibody

DF8746 200ul
EUR 420

anti- Antibody^Polyclonal antibody control antibody

LSMab09882 100 ug
EUR 525.6

ARHGDIA Antibody / RHOGDI Antibody

F54788-0.08ML 0.08 ml
EUR 165

ARHGDIA Antibody / RHOGDI Antibody

F54788-0.4ML 0.4 ml
EUR 379

Antibody

A1360-500 Ask for price

Anti-Glycolipid Antibody (AGA) Antibody

20-abx004855
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Ly1 Antibody Reactive (LYAR) Antibody

20-abx008109
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Ly1 Antibody Reactive (LYAR) Antibody

20-abx123734
  • EUR 493.20
  • EUR 710.40
  • 100 ul
  • 200 ul

Ly1 Antibody Reactive (LYAR) Antibody

20-abx014333
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Ly1 Antibody Reactive (LYAR) Antibody

abx033330-400ul 400 ul
EUR 627.6

Ly1 Antibody Reactive (LYAR) Antibody

abx033330-80l 80 µl
EUR 343.2

Anti-Glycolipid Antibody (AGA) Antibody

abx036399-100ug 100 ug
EUR 469.2

Anti-Glycoprotein Antibody (GP) Antibody

20-abx319900
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody

20-abx319901
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody

20-abx319905
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody

20-abx319913
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycolipid Antibody (AGA) Antibody

abx230204-100ug 100 ug
EUR 577.2

Ly1 Antibody Reactive (LYAR) Antibody

20-abx324434
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Ly1 Antibody Reactive (LYAR) Antibody

20-abx311665
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Ly1 Antibody Reactive (LYAR) Antibody

abx234901-100ug 100 ug
EUR 661.2

Anti-Anti-SEPT6 antibody antibody

STJ11100949 100 µl
EUR 332.4
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

Anti-Anti-SEPT9 Antibody antibody

STJ111369 100 µl
EUR 332.4
Description: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.

Anti-Anti-SEPT11 Antibody antibody

STJ111530 100 µl
EUR 332.4

Anti-Anti-SEPT4 Antibody antibody

STJ112276 100 µl
EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer.

Anti-Anti-MARCH9 Antibody antibody

STJ112609 100 µl
EUR 332.4

Anti-Anti-SEPT11 Antibody antibody

STJ113941 100 µl
EUR 332.4

Anti-Anti-SEPT11 Antibody antibody

STJ114081 100 µl
EUR 332.4

Anti-Anti-SEPT5 Antibody antibody

STJ114819 100 µl
EUR 332.4
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-MARCH8 Antibody antibody

STJ114828 100 µl
EUR 332.4

Anti-Anti-SEPT7 Antibody antibody

STJ116214 100 µl
EUR 332.4
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT8 Antibody antibody

STJ117206 100 µl
EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT12 Antibody antibody

STJ117759 100 µl
EUR 332.4
Description: This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-MARCH6 Antibody antibody

STJ118549 100 µl
EUR 332.4

Anti-Anti-MARCH6 Antibody antibody

STJ118550 100 µl
EUR 332.4

Anti-Anti-MARCH7 Antibody antibody

STJ118752 100 µl
EUR 332.4

Anti-Anti-SEPT3 Antibody antibody

STJ118990 100 µl
EUR 332.4

Anti-Anti-SEPT2 Antibody antibody

STJ28365 100 µl
EUR 332.4

Anti-Anti-SEPT7 Antibody antibody

STJ28963 100 µl
EUR 332.4
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT2 Antibody antibody

STJ25475 100 µl
EUR 332.4

Anti-Anti-SEPT5 Antibody antibody

STJ25477 100 µl
EUR 332.4
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-SEPT8 Antibody antibody

STJ25479 100 µl
EUR 332.4
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT1 antibody antibody

STJ119580 100 µl
EUR 332.4
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]

CLCN5 Antibody / CIC-5 antibody

RQ6462 100ug
EUR 419
Description: The CLCN5 gene encodes the chloride channel Cl-/H+ exchanger ClC-5. This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.

Cytokeratin 7 antibody-Cytoskeleton Marker Antibody

48169-100ul 100ul
EUR 399.6

Cytokeratin 7 antibody-Cytoskeleton Marker Antibody

48169-50ul 50ul
EUR 286.8

Anti CD22 Antibody: CD22 Monoclonal Antibody

065-A-01mg 0,1 mg
EUR 321
Description: anti-CD22 monoclonal antibody

Anti CD22 Antibody: CD22 Monoclonal Antibody

065-A-1000ug 1000 ug
EUR 1539
Description: anti-CD22 monoclonal antibody

Antibody Pair to ApoA-V antibody

10R-1876 100 ul
EUR 781.2
Description: Mouse monoclonal Antibody Pair to ApoA-V antibody

Ly1 Antibody Reactive Homolog (LYAR) Antibody

20-abx103034
  • EUR 543.60
  • EUR 159.60
  • EUR 1562.40
  • EUR 744.00
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Ly1 Antibody Reactive Homolog (LYAR) Antibody

20-abx103035
  • EUR 560.40
  • EUR 159.60
  • EUR 1612.80
  • EUR 760.80
  • EUR 410.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Ly1 Antibody Reactive Homolog (LYAR) Antibody

20-abx103036
  • EUR 577.20
  • EUR 159.60
  • EUR 1696.80
  • EUR 794.40
  • EUR 427.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Hepatitis C Virus Antibody (HCV) Antibody

abx023924-1mg 1 mg
EUR 1446

Anti-Glycoprotein Antibody (GP) Antibody (HRP)

20-abx319902
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (FITC)

20-abx319903
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (Biotin)

20-abx319904
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (HRP)

20-abx319906
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (FITC)

20-abx319907
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (Biotin)

20-abx319908
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (HRP)

20-abx319914
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (FITC)

20-abx319915
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (Biotin)

20-abx319916
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (HRP)

20-abx319929
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (FITC)

20-abx319930
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody (Biotin)

20-abx319931
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Ly1 Antibody Reactive (LYAR) Antibody (HRP)

20-abx311666
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Ly1 Antibody Reactive (LYAR) Antibody (FITC)

20-abx311667
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Ly1 Antibody Reactive (LYAR) Antibody (Biotin)

20-abx311668
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein 210 Antibody (gp210) Antibody

abx233571-100ug 100 ug
EUR 577.2

Anti Deoxyribonucleic Acid Antibody (DNA) Antibody

abx411057-50ug 50 ug
EUR 710.4

Monoclonal NGF/proNGF Neutralizing Antibody Antibody

AMM06679G 0.05mg
EUR 633.6
Description: A Monoclonal antibody against Human NGF/proNGF Neutralizing. The antibodies are raised in Mouse. This antibody is applicable in E

Goat anti- human Antibody^Polyclonal antibody

LSMab09896 100 ug
EUR 525.6

Antibody for Human alpha Tubulin Antibody

SPC-692D 0.1mg
EUR 424.8
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is unconjugated.

Antibody for Human alpha Tubulin Antibody

SPC-692D-A390 0.1mg
EUR 481.2
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 390.

Antibody for Human alpha Tubulin Antibody

SPC-692D-A488 0.1mg
EUR 480
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 488.

Antibody for Human alpha Tubulin Antibody

SPC-692D-A565 0.1mg
EUR 480
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 565.

Antibody for Human alpha Tubulin Antibody

SPC-692D-A594 0.1mg
EUR 480
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 594.

Antibody for Human alpha Tubulin Antibody

SPC-692D-A633 0.1mg
EUR 480
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 633.

Antibody for Human alpha Tubulin Antibody

SPC-692D-A655 0.1mg
EUR 480
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 655.

Antibody for Human alpha Tubulin Antibody

SPC-692D-A680 0.1mg
EUR 480
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 680.

Antibody for Human alpha Tubulin Antibody

SPC-692D-A700 0.1mg
EUR 480
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 700.

Antibody for Human alpha Tubulin Antibody

SPC-692D-ALP 0.1mg
EUR 472.8
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to Alkaline Phosphatase.

Antibody for Human alpha Tubulin Antibody

SPC-692D-APC 0.1mg
EUR 478.8
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to APC .

Antibody for Human alpha Tubulin Antibody

SPC-692D-APCCY7 0.1mg
EUR 565.2
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to APC/Cy7.

Antibody for Human alpha Tubulin Antibody

SPC-692D-BI 0.1mg
EUR 475.2
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to Biotin.

Antibody for Human alpha Tubulin Antibody

SPC-692D-DY350 0.1mg
EUR 496.8
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to Dylight 350.

Antibody for Human alpha Tubulin Antibody

SPC-692D-DY405 0.1mg
EUR 483.6
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to Dylight 405.

Antibody for Human alpha Tubulin Antibody

SPC-692D-DY488 0.1mg
EUR 471.6
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to Dylight 488.
No variations had been discovered for the forms of CT requests between the two years. The median age of receivers of vascular tissues was 69.6 ± 14.6 years within the 2019 and 63.3 ± 14.9 years in 2020 (p < 0.01). The median age of receivers of pulmonary and aortic valves didn’t differ between the two years (9.32 ± 11.49 vs. 8.36 ± 10.66 and 48.67 ± 27.19 vs. 37.14 ± 31.97 respectively). Regardless of the dramatically discount of donors, the variety of CT collected has not decreased considerably and to this point the CT distribution charge is corresponding to these of 2019.

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