NEDD4-like ubiquitin ligase 2 protein (NEDL2) in porcine spermatozoa, oocytes, and preimplantation embryos and its role in oocyte fertilization†

NEDD4-like ubiquitin ligase 2 protein (NEDL2) in porcine spermatozoa, oocytes, and preimplantation embryos and its role in oocyte fertilization†

The ubiquitin-proteasome system performs various regulatory and homeostatic roles in mammalian copy. Ubiquitin ligases are the substrate-specific mediators of ubiquitin-binding to its substrate proteins. The NEDD4-like ubiquitin ligase 2 (aliases NEDL2, HECW2) is a HECT-type ubiquitin ligase that incorporates one N-terminal HECW ubiquitin ligase area, one C-terminal HECT ubiquitin ligase area, one C2 area, and two…

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Neutralization of SARS-CoV-2 pseudovirus using ACE2-engineered extracellular vesicles

Neutralization of SARS-CoV-2 pseudovirus using ACE2-engineered extracellular vesicles

The unfold of coronavirus illness 2019 (COVID-19) all through the world has resulted in anxious healthcare burdens and international well being crises. Creating an efficient measure to guard individuals from an infection is an pressing want. The blockage of interplay between angiotensin-converting enzyme 2 (ACE2) and S protein is taken into account an important goal…

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