CIDRZ-UAB Prevention and Treatment Service Units

Category 3

The Centre for Infectious Disease Research in Zambia (CIDRZ) is a nonprofit organization affiliated with the University of Alabama at Birmingham (UAB). A large organization of nearly 600 employees, CIDRZ is a major government partner for HIV service expansion and clinical research in Zambia. The CIDRZ HIV prevention and treatment service units support 274 public health facilities in four of the nine provinces of Zambia. Prevention of mother-to-child HIV transmission (PMTCT) services are offered in 253 clinics and hospitals. Since the program began in 2001, 570,000 women have been counseled, with 480,000 tested and 90,000 found HIV-positive. We have provided maternal antiretroviral drug prophylaxis to 81,000 HIV-positive women. The PMTCT team has trained 2,069 nurses and midwives to date. HIV care and treatment services are offered in 58 sites. The Program has trained 2,376 health care workers and counselors in HIV care: 1,222 in HIV clinical management, 654 in pediatric HIV clinical management, and 500 in adherence counseling. Since the program began in 2004, 145,000 people have received HIV care, with 92,000 starting antiretroviral therapy. Our related service activities include a comprehensive cervical cancer screening program that has screened 20,000 women, and an integrated TB/HIV program that offers HIV testing to TB patients and TB screening for all HIV patients.

Goal of the Practice
  • In 2008, CIDRZ/UAB objectives included: Enroll 146,000 adults into care in 70 treatment sites;
  • Develop concrete systems to improve linkages between ART and PMTCT programs;
  • Implement a Pilot Integrated Services Model in two sites;
  • Expand Cervical Cancer Project from 12 to 24 clinics;
  • Continue progress on six public health evaluations (PHE's).
Core Components
  • PMTCT Services/ Care and Support
  • HIV clinical management for adults and children/ ART and adherence counseling
  • Integrated models of care
  • TB and cervical cancer screening
  • Research/ Public health evaluations
Noteworthy Results
  • Served 145,000 PLWH including 92,000 on Art Provided PMTCT services to 480,000 pregnant women with 81,000 of the 90,000hiv (+) receiving maternal ARV drug prophylaxis.
  • Trained over 2000 health care workers.
  • Increase in CD4 % in children treated from mean of 12.9% to 23.7% at 6 months, 27.0%at 12 months, 28.0% and 28.4% at 24 months. Since starting, 5% had withdrawn from care and 13% were >30 days late for their last appointment.
  • Early program outcomes (2006 report) found a 90% of patients were adhering to their ART treatment after 12 months, with increase in CD4 count of 175/ul.
Focus Areas
Implemented By
Centre for Infectious Disease Research-Zambia (CIDRZ)
Participating Organization
  • University of Alabama at Birmingham (UAB)
  • Ministry of Health
Clinic/Health facility
Target Population
  • Infants (newborn to 24 months)
  • Females
  • General Public
  • People Living with HIV (PLWH)
> 50000
Implementation Years
01/2010 - ongoing